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H. Robert Silverstein, MD's avatar

NOT LIKELY A BIG MYSTERY: I would bet that the most active intake more animal protein with leucine (BCAA) and saturated fat causing inflammatory mTOR activation and cholesterol production -> cor ASCVD/calcification. HRS, MD, FACC

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vibhawari pal's avatar

Nice article ❤️

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Samuel Mann's avatar

Hi Paul.

Thank you for your article.

I obtained a CAC score just to screen, and the score was 1600. No symptoms. Finished second in my age group in the 5th Ave mile, at age 77.

Main renal artery score 0. 3-400 in the other cornonary arteries.

I would offer 2 comments:

1. I did marathons for only 3 years, and since then 4 miles or less 4 times a week, but always at a vigorous pace. Studies seem to show that intense running is more closely associated with CAC than is long slower distance running.

2.Do you see any publications that consider the role of the substantially increased intake of food and particularly carbs as a result of the expenditure of so many calories with exercise?

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Chris Fehr's avatar

Not a doctor but I too have wondered if the increased food intake to be what sounds like an elite athlete could be a risk.

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Richard Sachs's avatar

“The idea that large amount of exercise might have deleterious cardiac effects is an apparent paradox.”

amen!

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Joshua Bonifacio's avatar

Great read, thank you.

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Jonida's avatar

Great post, as always🙂

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